While the 2025 MLB season technically got underway last week with the two-game “Tokyo Series” in Japan, traditional Opening Day will take place this week.

The first pitch of Opening Day for most teams will be Thursday, with the Philadelphia Phillies set to start the season the road in a quest for the franchise’s third World Series Title.

Here’s what you need to know about Opening Day 2025:

When is Opening Day for MLB?

The MLB season kicked off with the Los Angeles Dodgers facing the Chicago Cubs in a two-game “Tokyo Series” in Japan, which started Tuesday, March 18. The Dodgers swept the two-games series.

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Traditional MLB Opening Day will be on Thursday, March 27, with 28 teams in action.

When is Phillies Opening Day 2025?

The Phillies will open the 2025 season in Washington against the Nationals on March 27.

Who is the Opening Day Phillies starter?

Phillies manager Rob Thomson announced that Zack Wheeler will start Opening Day against the Nationals. It will be Wheeler’s second straight Opening Day start for the Phils.

When is Phillies’ home opener in 2025?

The Phillies will hold their home opener at Citizen Bank Park on March 31. The Phillies will open against the Colorado Rockies.

Philadelphia’s first home weekend series will be April 4-6 against the Dodgers.

Phillies Opening Day roster

Catcher: J.T. Realmuto, Rafael Marchán

First base: Bryce Harper

Second base: Bryson Stott

Shortstop: Trea Turner

Third base: Alec Bohm

Outfielder: Nick Castellanos, Max Kepler, Brandon Marsh, Johan Rojas

Designated hitter: Kyle Schwarber

Bench: Kody Clemens and Edmundo Sosa

Starting pitchers: Jesús Luzardo

, Aaron Nola, Cristopher Sánchez

, Taijuan Walker and Zack Wheeler

Bullpen: José Alvarado

, Tanner Banks, Carlos Hernández

, Orion Kerkering, Jordan Romano, Joe Ross, José Ruiz

and Matt Strahm.

*Starting pitcher Ranger Suárez

and outfielder Weston Wilson will open the season on the injured list.

Projected Phillies Opening Day lineup

1. Trea Turner, SS
2. Bryce Harper, 1B
3. Alec Bohm, 3B
4. Kyle Schwarber, DH
5. J.T. Realmuto, C
6. Max Kepler, LF
7. Nick Castellanos, RF
8. Bryson Stott, 2B
9. Brandon Marsh, CF

2025 World Series odds

Here are the latest World Series odds as of Monday, March 24:

• Dodgers (+240)
• Braves (+900)
• Yankees (+900)
• Phillies (+1100)
• Mets (+1200)
• Orioles (+1600)
• Red Sox (+1800)
• Astros (+1800)
• Rangers (+2200)
• Diamondbacks (+3000)
• Cubs (+3000)
• Tigers (+3000)
• Twins (+3000)
• Mariners (+3000)
• Padres (+3000)
• Guardians (+3500)
• Royals (+4000)
• Brewers (+5000)
• Rays (+5000)
• Blue Jays (+6600)
• Reds (+8000)
• Giants (+8000)
• Pirates (+12500)
• Cardinals (+12500)
• Athletics (+20000)
• Nationals (+20000)
• Angels (+25000)
• White Sox (+50000)
• Rockies (+50000)
• Marlins (+50000)

All odds via BetMGM.