The No. 2 seed Tennessee Volunteers will try to secure their first Final Four appearance in school history when they face the No. 1 seed Houston Cougars on Sunday afternoon in the Elite Eight of the 2025 NCAA Tournament. Tennessee avenged a pair of regular-season losses with a 78-65 win over No. 3 seed Kentucky on Friday night. Houston, which is in the Elite Eight for the third time in five years, is coming off a 62-60 win over No. 4 seed Purdue. The Cougars executed a beautiful inbound play to score the game-winning bucket with less than one second remaining. Guard Mylik Wilson is listed as questionable for the Cougars. 

Tip-off from Lucas Oil Stadium in Indianapolis is set for 2:20 p.m. ET. Houston is a 2.5-point favorite in the latest Tennessee vs. Houston odds from SportsLine consensus, while the over/under for total points scored is 125.5. Houston is a -154 favorite on the money line.

Before making any Tennessee vs. Houston picks, you won’t want to miss the college basketball predictions from college basketball expert Micah Roberts.

Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos’ book director. Armed with an elaborate network of sources, Roberts has unmatched info in multiple sports. Over the past three college basketball seasons, Roberts is 267-227, returning $1,578 to $100 players.

Roberts enters the Elite Eight of the 2025 NCAA Tournament on a 15-5-1 roll (+917) over his last 21 college basketball picks involving Houston, and he is 11-3 (+769) in his last 14 involving Tennessee. Anybody who’s followed his picks could be WAY UP!

For Tennessee vs. Houston, Roberts is leaning Under on the total and he also found a critical X-factor that has him jumping on one side of the spread. You ABSOLUTELY NEED to see these picks before locking in any 2025 NCAA Tournament picks of your own.

So who wins Tennessee vs. Houston, and which side of the spread should you back? Join SportsLine right now to see which side of the spread you need to jump on, all from a red-hot college basketball expert that is on a 15-5-1 (+917) run on his CBB picks involving Houston!