Elsewhere, Potter retains the same nine players who started last Sunday’s 1-1 draw at Aston Villa.
Alphonse Areola starts in goal, with the 31-year-old seeking an 18th Premier League clean sheet on what is his 86th appearance for the Hammers.
What looks like a back five will be unchanged from Villa Park. The defence will be anchored by centre-backs Maximilian Kilman, Vladimír Coufal and Aaron Cresswell, while Aaron Wan-Bissaka and Emerson occupy the defensive flanks.
Irving plays in midfield alongside Tomáš Souček and Carlos Soler. Souček has two goals and two assists in eleven career appearances against Chelsea in Claret and Blue.
Mohammed Kudus, who has completed a top-flight high 57 dribbles so far this season, will play in a more advanced role with skipper Bowen.
Among the substitutes, meanwhile, defender Dinos Mavropanos returns from a one-match suspension and is included on the nine-man bench.
Alongside Mavropanos will be goalkeepers Łukasz Fabiański and Wes Foderingham, Academy of Football graduate trio Kaelan Casey, Ollie Scarles and Lewis Orford, midfielders Guido Rodríguez and Luis Guilherme and forward Danny Ings.
Chelsea: Jörgensen, James ©, Tosin, Colwill, Cucurella, Caicedo, Fernández, Madueke, Palmer, Sancho, Jackson
Subs: Sánchez (GK), Gusto, George, Acheampong, Chalobah, Dewsbury-Hall, Guiu, Neto, Nkunku
West Ham United: Areola, Wan-Bissaka, Coufal, Kilman, Cresswell, Emerson, Rodríguez, Souček, Soler, Kudus, Bowen ©
Subs: Fabiański (GK), Foderingham (GK), Scarles, Casey, Orford, Irving, Luis Guilherme, Ings
Referee: Stuart Attwell
