Knicks vs. Pistons odds, line, spread, start time: 2025 NBA picks, April 10 predictions from proven model

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The New York Knicks (50-29) will try to clinch the No. 3 seed in the Eastern Conference when they face the Detroit Pistons (43-36) on Thursday night. New York had its two-game winning streak snapped in an overtime loss to Boston on Tuesday, but it still holds a two-game lead over Indiana with three games remaining. Detroit has lost four of its last five games, falling to Sacramento in a 127-117 final on Monday. This game likely serves as a first-round playoff preview, as the Knicks and Pistons are projected to play each other in the 3 vs. 6 matchup.

Tipoff from Little Caesars Arena is set for 7 p.m. ET. The Pistons are favored by 3.5 points in the latest Pistons vs. Knicks odds via SportsLine consensus, while the over/under is 228.5 points. Before entering any Knicks vs. Pistons picks, you’ll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the final week of the 2024-25 NBA regular season on a sizzling 155-115 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It’s also an outstanding 21-10 (68%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Detroit vs. New York. You can head to SportsLine to see its picks. Here are several NBA betting lines for the game:

Pistons vs. Knicks spread: Pistons -3.5 at Caesars Sportsbook
Pistons vs. Knicks over/under: 228.5 points
Pistons vs. Knicks money line: Pistons: -163, Knicks: +136
Pistons vs. Knicks picks: See picks here
Pistons vs. Knicks streaming: FuboTV (Try for free)

Why the Pistons can cover

Detroit lost 16 consecutive games to New York across multiple seasons, with the final loss coming on Nov. 1 of this season. However, the Pistons snapped the streak with a 120-111 win in New York on Dec. 7, and they added a 124-119 road win on Jan. 13. Cade Cunningham is averaging 29.0 points, 8.3 assists and 6.0 rebounds against the Knicks this season.

The Pistons have lost four of their last five games, but they have been able to rest since Monday’s loss to Sacramento. They blew an 18-point lead in that contest, getting outscored 65-45 in the second half. Cunningham had 35 points, upping his season average to 25.9 points per game. See which team to pick here.

Why the Knicks can cover

New York would like to clinch the No. 3 seed in the conference while also re-establishing control of this series before their expected playoff matchup. The Knicks are in better form than the Pistons, having won seven of their last 10 games. They notched back-to-back wins against the Hawks and Suns last weekend, winning both of those games by 14-plus points.

Their two-game winning streak was halted in an overtime loss to Boston on Tuesday in a game that landed exactly on the spread (2). Forward Karl-Anthony Towns led New York with 34 points and 14 rebounds, while point guard Jalen Brunson had 27 points and 10 assists. Josh Hart also posted a double-double for the Knicks, finishing with 10 points and 11 rebounds. See which team to pick here.

How to make Pistons vs. Knicks picks

The model has simulated Knicks vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning Under the total, and it’s also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Knicks, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.