The men’s NCAA Tournament heated up with the highly anticipated Sweet 16 showdown between the No. 4 Purdue Boilermakers and the No. 1 Houston Cougars.

Houston’s last-second 62-60 victory advanced it to the Elite Eight, where it will take on No. 2 Tennessee.

More: Who’s left in men’s March Madness? Bracket updates, schedule, predictions

Purdue’s journey to the Sweet 16 was nothing short of thrilling. They rallied to defeat No. 13 seed High Point, 75-63, with Trey Kaufman-Renn leading the charge with 21 points and eight rebounds. Their momentum continued in the second round as they secured a 76-62 victory against No. 12 seed McNeese.

Top-seeded Houston has been a force to be reckoned with in the tournament. They cruised past No. 15 seed SIU Edwardsville 78-40 in the first round, setting the tone for their dominance. In the Round of 32, they held off a fierce comeback attempt by the Gonzaga Bulldogs, winning 81-76. J’Wan Roberts led the Cougars in scoring with 18 points, eight rebounds, and five assists.

FOLLOW THE MADNESS: NCAA men’s tournament bracket, scores, schedules, teams and more.

Here is how No. 4 Purdue and No. 1 Houston’s game played out:

Houston vs Purdue score

Houston came away with a 62-60 victory against Purdue in the Sweet 16 of the 2025 NCAA Tournament at Lucas Oil Stadium in Indianapolis, a de-facto road game for the Cougars given the close geographic proximity of their opponent.

Houston led by 10 with seven minutes remaining, but was staring down the possibility of overtime with the score tied at 60 and only two seconds remaining. However, Cougars coach Kelvin Sampson drew up a masterful baseline out of bounds play, with Milos Uzan dishing it to Joseph Tugler, who passed it right back to an open Uzan for a layup with 0.9 seconds left.

Houston vs. Purdue highlights

Here’s a look at some of the biggest plays from Houston’s win over Purdue:

Where to watch Purdue vs. Houston: TV channel, time, live stream

• Game Day: Friday, March 28, 2025
• Game Time: 10:09 p.m. ET
• Location: Lucas Oil Stadium (Indianapolis)
• TV Channel: TBS
• Live Stream: Fubo

Watch Purdue vs. Houston on Fubo (free trial)

Purdue vs. Houston odds

Odds via BetMGM as of Thursday, March 27.

• Spread: Houston (-8.5)
• Moneyline Favorite: Houston (-425)
• Moneyline Underdog: Purdue (+340)
• Total: 132.5

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