Giants vs. Astros Prediction, Odds, Picks - April 1

Data Skrive

Willy Adames and the San Francisco Giants play the Houston Astros on Tuesday at Daikin Park. Hayden Wesneski will start for Houston, with first pitch at 8:10 p.m. ET. Oddsmakers list the Giants as -119 moneyline favorites, while giving the underdog Astros -101 moneyline odds to win. San Francisco is a 1.5-run favorite (at +142 odds). The matchup’s total is set at 8 runs.

Here is everything you need to know from a betting perspective on the Giants-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Houston Astros’ Spencer Arrighetti spoke with John Smoltz after his dominant performance against the New York Mets.

Giants vs. Astros Game Information & Odds

When: Tuesday, April 1, 2025 at 8:10 p.m. ET
Where: Daikin Park in Houston, Texas
How to watch on TV: SCHN and NBCS-BA+

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Giants -119 -101 8 -115 -105 -1.5 +142 -169

Giants vs. Astros Prediction

Score Prediction: Giants 4, Astros 3
Total Prediction: Under 8 runs
Win Probabilities: Giants 52%, Astros 48%

Giants vs. Astros Betting Insights

The Giants went 46-34 in games they were favored on the moneyline last season (winning 57.5% of those games).
San Francisco had a record of 39-28 when playing as a moneyline favorite with odds of -119 or shorter last year (58.2%).
The Giants have an implied moneyline win probability of 54.3% in this matchup.
The Astros were underdogs in 44 games last season and won 21 (47.7%) of those contests.

Giants Player Insights

Adames slugged 32 home runs and collected 112 RBI last season while batting .251.
Matt Chapman collected 142 hits, posted an OBP of .328, and a .463 SLG.
Heliot Ramos hit .269 last season with 22 home runs and 72 RBI.
Mike Yastrzemski collected 99 hits, posted an OBP of .302 and a .437 SLG.

Astros Player Insights

Yordan Alvarez racked up a batting average of .308, with 35 home runs and 86 runs batted in last season.
Jose Altuve hit .295 with 31 doubles, 20 home runs and 47 walks.
Yainer Diaz hit .299 last season with 29 doubles, three triples, 16 home runs and 24 walks.
Isaac Paredes hit .238 with 25 doubles, a triple, 19 home runs and 76 walks.

Houston Astros’ Spencer Arrighetti spoke with John Smoltz after his dominant performance against the New York Mets.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.