The No. 3 seed New York Knicks will try to take a commanding lead in their first-round series against the No. 6 seed Detroit Pistons when they meet in Game 4 Sunday afternoon. Detroit bounced back from a Game 1 loss with a 100-94 win in Game 2, but New York regained the series advantage with a 118-116 win in Game 3. The series will shift back to Madison Square Garden for Game 5 Tuesday. 

Tipoff from Little Caesars Arena in Detroit is set for 1 p.m. ET Sunday. The Pistons are 2-point favorites in the latest Pistons vs. Knicks odds via SportsLine consensus, while the over/under for total points scored is 217. The Pistons are -134 on the money line (risk $134 to win $100), while the Knicks are +114 (risk $100 to win $114). 

Before making any Knicks vs. Pistons picks, check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the first full week of the 2025 NBA playoffs on a sizzling 156-116 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It is also 22-11 (67%) on top-rated NBA against-the-spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Pistons vs. Knicks 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it also says one side of the spread hits in over 50% of simulations.