76ers vs. Wizards odds, line, spread: 2025 NBA picks, March 26 predictions from proven model

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The Philadelphia 76ers are set to host the Washington Wizards for an Eastern Conference bout on Wednesday. Philadelphia is 23-49 overall and 12-22 at home, while Washington is 15-56 overall and 8-28 on the road. The Sixers have won 16 of their last 18 home games against the Wizards but enter Wednesday’s contest on a five-game losing streak. Philadelphia will be without several of its stars on Wednesday, including Joel Embiid (knee), Paul George (groin), Tyrese Maxey (finger), Kelly Oubre Jr. (knee) and Lonnie Walker IV (neck). 

Tipoff from Wells Fargo Center is at 7 p.m. ET. The 76ers are favored by 3.5 points in the latest 76ers vs. Wizards odds, while the over/under is 230.5 points. Before entering any Wizards vs. 76ers picks, you’ll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 23 of the 2024-25 NBA season on a sizzling 153-113 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It’s also an outstanding 20-10 (67%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Washington vs. Philadelphia. You can head to SportsLine to see its picks. Here are several NBA betting lines for the game:

  • 76ers vs. Wizards spread: 76ers -3.5 at DraftKings Sportsbook
  • 76ers vs. Wizards over/under: 230.5 points
  • 76ers vs. Wizards money line: 76ers: -154, Wizards: +129
  • 76ers vs. Wizards picks: See picks here
  • 76ers vs. Wizards streaming: FuboTV (try for free)

Why the 76ers can cover 

The 76ers are headed into Wednesday’s matchup looking for a big change in momentum after dropping their fifth straight game on Monday. They fell 112-99 to the Pelicans. Forward Justin Edwards was effective in the loss, finishing with 19 points, three rebounds and two assists. Edwards has now scored 19 or more points in four consecutive games. 

Philadelphia has won six straight against Washington, and the Wizards are the worst team in the Eastern Conference. Washington is also 1-5 against the spread in its last six games against an opponent from the East. The Wizards are giving up 120.5 points per game, which ranks dead last in the NBA. See which team to pick here

Why the Wizards can cover 

Meanwhile, the point spread may have favored the Wizards on Monday, but the final score did not. They took a 112-104 hit to the loss column at the hands of the Raptors. Washington can’t catch a break and has now endured five losses in a row.

Guard Jordan Poole is the main playmaker for this offense, leading the team in points (20.5) and assists (4.5) per game. He’s connecting on 42.6% of his field goals and 37.5% of his 3-point attempts, which is the best mark of his career. In addition, the 76ers are 2-8 against the spread in their last 10 games at home. See which team to pick here

How to make 76ers vs. Wizards picks

The model has simulated 76ers vs. Wizards 10,000 times and the results are in. We can tell you that the model is leaning Under the total, and it’s also generated a point-spread pick that hits in over 60% of simulations. You can only see the pick at SportsLine.

So who wins Wizards vs. 76ers, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that is on a 153-113 roll on top-rated NBA picks since last season, and find out.

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